Intruder breaks into front door of home. I point pistol at him. He runs away (or stays until the cops arrive, kinda his choice). Odds of anyone being physically injured? Very small.
Assuming the home invader is unarmed and you are there with your pistol waiting for him to bust your door down.
Otherwise, he just shoots you as you go for your gun hidden away in the side table of your bedroom or the drawer in the desk of your in home office.