I think one of the concerns is going to be prosthetic upgrading. We're capable of making prosthetic limbs that are far superior to our natural limbs the only real barrier is our control over said limbs. Given technological telepathy you could replace your arms/legs with super strength, bulletproof, fireproof, supersensitive, superfast versions and control them with perfect precision.
Why bother grafting them to you and chopping an arm off? The technology allows you to remotely control things.