In the beginning of all ATHF episodes, except for the "The Last F*cking One for 2003", have a strange, awkward beginning with a scientist and his assistant that usually has some sort of relevance to the episode.
My favorite:
Dr. Wierd: "GENTLEMEN, BEHOLD! I... have lost weight!"
Assistant: "He-hey! Looking good!"
Dr. Wierd: "Yes... uhh... all sugars, gone. MANUALLY! WITH THIS!"
*Pulls out a bloody chainsaw and revs it, revealing that he cut off all the flesh and muscle from his knees down*
Assistant: "Okay... I think I'm gonna go to lunch..."
Dr. Wierd: "I need to lose 20 more pounds, or else I'll never be pretty!"
*continues to chainsaw his legs*
What's yours?