I don't believe it would. You have to remember that the OH damage is mitigated (to 50%, I think). You simply won't get the big hits with your OH that you will with your MH. Of course, you get less damage from the faster weapons, too, but as Evilgrinn pointed out, there is also the Flurry and UR to consider. I think that alone would make the faster hits more desireable than the bigger hits, in terms of overall damage.