Just finished Mushishi, and really enjoyed it. I can't tell if the lack of an overarching plotline and the episodic nature of the chapters made the story better or not, but it worked well. The manga revolves around Mushi, which are technically translated as "insects," I believe. Mushi are elemental organisms that exhibit almost supernatural powers and are all throughout the world, but invisible to most people. Most chapters follow the protagonist, Ginko, a Mushishi or Mushi Master, who comes across someone suffering from a mushi-related issue. Ginko himself is mostly just a vessel for moving the story forward; there are a couple chapters talking about his past, but most of them focus on the people who are having mushi problems. Even though the formula is the same, each chapter has different mushi and focuses primarily on that episode's characters. Each mushi is very different, and some of harmless, some are harmful, and some are in between; this means some of the stories are happy, some are tragic, and many are a mixture between the two.
I really recommend it, I liked the pacing. If I had one issue, it's that the series ended just like it progressed: the final chapter was just another chapter. Kinda makes it feel incomplete.