I think once we get to the point that there are commercially viable business opportunities in space we're going to see a space boom like we couldn't imagine. There's no unsolvable technical reason we can't populate the solar system using current knowledge we just don't have enough of a reason to do it at the moment. The second we do everyone and their mother is going to be developing space tech.
If you can build a smelter and factory in space and have the capability to rope asteroids you really have no limits to what you can accomplish given enough time. We're really not that far off of that.