Like Xilk said, you don't need to overkill anything. If I can still one-shot with minikin, I use it so I don't even have to give a second thought to MP or restore chests if I don't want to use the keys. (I usually just open all the blue boxes anyway.)
Generally, I'll see how I do without enervation/tonic(or memento mori)/fantod, etc. Then if I'm short, I'll start working buffs/debuffs in until I have to do as little as possible per pull. It gets very, very mind numbing after awhile, and the fewer steps, the longer I can go without burning out. http://www.ffxiah.com/item-sets/229872
is my set, and it's by no means the best. It's pretty similar to Sebastion's, so you can extrapolate from the two of them what's good to use. Things like rajas and cuchulain's belt aren't best in slot, but they save inventory and, again, it doesn't matter as long as you can one-shot the group. I know, NQ ocelomeh. Not bothering unless I get Toci's.
Edit: Those atma are pretty standard. You won't have a very good time without at least Lion or Blinding Horn. Razed Ruins is actually better than Minikin. I'm not sure whether Baying Moon's +30 MAB would be better than RR's dex, to be honest. It would depend on how much MAB you already have. Hell's Guardian has the same +50 as Ultimate, but Proto-Ultima is easier than Pandemonium Warden, I would think. Edited, Aug 28th 2012 4:32pm by zellbaca
Louverance: You should spend your next life as a friar, my friend! Later...
Meransarget: Oh, herro there.