There's no real need to optimize specs anymore--you'll go through everything ludicrously fast in any case. Instead choose how you like to play.
I'm partial to the "run around, dot everything, laugh maniacally" style, so Afflic would work well. Or Demo, because you can get more stam and a VW to grab the things your dots are killing. :P
In any case, everything's gonna die in a few casts anyway.
Anyways, you all are horrible, @#%^ed up people