I took it for about two years, and just stopped it a couple of months ago. It does work, there were times during that two year period that I stopped it because, like Aeth, I hate taking medication, but I definitely felt myself spiraling down when I did stop it. And it definitely increased my appetite, although it could have been an idiosyncratic reaction in my case. I've lost weight since stopping it and I stopped taking it now because I no longer need it (although I have returned to WoW, and trade chat is having its effect on me . . .).
I don't know where my aversion to taking medication comes from since my undergraduate degree is a B.S. Pharmacy, but the only drug I take regularly now is Ibuprofen. Aspirin, by the way, is a miracle drug. Ibuprofen, being Aspirin's grandchild, is quite close to miracle status.
Aspirin is excellent for headaches, arthritis, general pain, fever, and is important for people who have had a heart attack and are prone to strokes. It "thins the blood" (a common fallacy - it inhibits clotting, the blood is not any thinner than before), and did I mention its great for fevers? Aspirin is by far the best fever reducing medication available. You cannot overdose on it, because you will vomit it back up before you take enough to even approach a lethal dose. Be careful, as with any medication, when administering it to children.
Oh, and I missed this yesterday - I grew up watching Mr. Wizard.