Stats don't really mean much to me without knowing the player equivalents. Yeah, those huge numbers look scary on paper, but if the expectation of entering Inferno would have players at something like 50k HP and 60% or more damage reduction, suddenly those numbers can be tolerable. Only real concern with that kind of stat bloat is it grossly trivializes the earlier difficulties to the point where a veteran of Inferno could make Hell seem like Normal.
Anyway, I'm not a fan of what Blizz did to Hell in D2 sometime back, what with basically guaranteeing every mob has at least one immunity and it becoming largely melee unfriendly unless you're dinging into gear you farmed up from a Sorc or Necro. I liken impenetrable defenses to overwhelming offense on the retarded balance scale, and there was no shortage of both there. Inferno seems to be poised to replicate similar, but I'm hoping it's more likely people will actually be able to experience it successfully than through oodles of frustration.