I was disappointed with Great Swords when I was leveling my Warrior. The swords got really expensive, and they didn't do as much damage as Hand-to-hand with a Monk sub. My WAR/MNK with H2H, +8 STR, Mithkabobs, Martial Arts, Counter, Double and sometimes berserk I did serious damage. I'd hit 2-3 times each round, and do %100-200 more damage then a WAR with a sword/axe. The TP builds like crazy, and with boosting before unleashing Combo I would hit between 100-200hp on toughs to ITs (often times hitting 300hp against easys to evens).
If you have a WAR/MNK you should seriously consider H2H weapons.